SUBCLINICAL INFLAMMATORY PROCESS IN FORMATION OF CARDIOVACULAR DISORDERS IN CHILDREN WITH OBESITY

Abstract

The problem of overweight and obesity in children requires constant study of its new aspects. According to modern requirements, for an adequate assessment of multifactorial changes in the metabolic status in obese patients, it is necessary to use data from immunological studies. The article presents the results of our own research on the level of markers of systemic inflammation and their influence on the formation of cardiovascular disorders in obese children. It was found that children with obesity and cardiovascular disorders have significantly higher values of inflammatory markers (IL-6 and CRP-hs) and low levels of the pro-inflammatory cytokine IL-10 (p <0.05), which indicates subclinical damage to the cardiovascular system and chronic inflammatory process in obese children. The features of the obtained correlation relationships confirm the involvement of a chronic inflammatory process in the formation of cardiovascular disorders in obesity in children.